Description

5-Bromo-2-Iodo-4-Methoxy-Benzoic Acid Methyl Ester is a high-purity, multi-halogenated aromatic building block of significant interest in advanced organic synthesis. Its value lies in the strategic positioning of bromine and iodine atoms on the methoxybenzoate scaffold, which allows for selective, sequential cross-coupling reactions. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly in drug discovery and material science applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in developing novel herbicides and fungicides, leveraging its halogenated structure for bioactivity.
• Material Science: Serves as a monomer or building block for creating specialized polymers and liquid crystals with unique electronic properties.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Sonogashira couplings, where the iodine and bromine offer differential reactivity.
• Chemical Biology: Utilized in synthesizing molecular probes and tags for studying biological processes.
• Academic & R&D: A valuable reagent for methodological development in synthetic organic chemistry laboratories worldwide.

Basic Information

Product Name	5-Bromo-2-Iodo-4-Methoxy-Benzoic Acid Methyl Ester
CAS No.	1379361-99-5
Molecular Formula	C9H8BrIO3
Molecular Weight	370.97 g/mol
Synonyms	Methyl 5-Bromo-2-Iodo-4-Methoxybenzoate; 4-Methoxy-5-bromo-2-iodobenzoic Acid Methyl Ester; Benzoic acid, 5-bromo-2-iodo-4-methoxy-, methyl ester; 5-Bromo-2-iodo-4-methoxybenzoic acid methyl ester; Methyl 4-methoxy-5-bromo-2-iodobenzoate; 2-Iodo-5-bromo-4-methoxybenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Iodo-4-Methoxy-Benzoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0% (Area Percent)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.