Description

Methyl 2-Bromo-4,6-Difluorobenzoate is a high-purity, multi-functional benzoate ester derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in providing a versatile halogenated and fluorinated aromatic building block, enabling precise molecular construction for complex target compounds. This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring difluorophenyl and bromo-substituted aromatic cores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the fluorine and bromine substituents modulate biological activity and stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for creating fluorinated aromatic components used in electronic display technologies and organic light-emitting diodes.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Functional Polymer Monomer: Acts as a monomer or modifier in the synthesis of specialty polymers with tailored thermal, optical, or chemical resistance properties.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	Methyl 2-Bromo-4,6-Difluorobenzoate
CAS No.	1379336-54-5
Molecular Formula	C8H5BrF2O2
Molecular Weight	251.03 g/mol
Synonyms	2-Bromo-4,6-difluorobenzoic acid methyl ester; Methyl 2-bromo-4,6-difluorobenzoate; Benzoic acid, 2-bromo-4,6-difluoro-, methyl ester; Methyl 2-bromo-4,6-difluorobenzoate; Methyl α-bromo-4,6-difluorobenzoate; 4,6-Difluoro-2-bromobenzoic acid methyl ester; Methyl 4,6-difluoro-2-bromobenzoate
EINECS	Contact for details

Quality Control

Our Methyl 2-Bromo-4,6-Difluorobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing batch-specific results are provided to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.