Description

3-Bromo-5-Iodo-2-Methyl Benzoic Acid Ethyl Ester is a high-purity, multi-halogenated aromatic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both bromine and iodine substituents, makes it a versatile precursor for constructing complex molecules via cross-coupling reactions. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in medicinal chemistry programs targeting complex small molecules.
• Agrochemical Synthesis: Serves as a building block for creating advanced herbicides, fungicides, and insecticides with specific halogenated aromatic cores.
• Material Science Research: Used in the synthesis of organic semiconductors, liquid crystals, and other functional materials where halogenated benzoic acid derivatives are required.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the presence of both bromo and iodo leaving groups.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in chemical manufacturing.
• Academic & Industrial R&D: A valuable reagent for exploratory chemistry in university laboratories and corporate R&D centers focused on synthetic methodology.

Basic Information

Product Name	3-Bromo-5-Iodo-2-Methyl Benzoic Acid Ethyl Ester
CAS No.	1379317-96-0
Molecular Formula	C10H10BrIO2
Molecular Weight	369.00 g/mol
Synonyms	Ethyl 3-Bromo-5-iodo-2-methylbenzoate; Benzoic acid, 3-bromo-5-iodo-2-methyl-, ethyl ester; 2-Methyl-3-bromo-5-iodobenzoic acid ethyl ester; 3-Bromo-5-iodo-o-toluic acid ethyl ester
EINECS	Contact for details

Quality Control

Our production of 3-Bromo-5-Iodo-2-Methyl Benzoic Acid Ethyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.