Description

5-Bromo-2-Ethoxyisonicotinic Acid is a high-purity, functionalized pyridine derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for drug discovery programs and the synthesis of active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials and functional polymers.
• Chemical Biology Probes: Utilized to develop molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	5-Bromo-2-Ethoxyisonicotinic Acid
CAS No.	1379305-67-5
Molecular Formula	C8H8BrNO3
Molecular Weight	246.06 g/mol
Synonyms	5-Bromo-2-ethoxy-4-pyridinecarboxylic acid; 2-Ethoxy-5-bromoisonicotinic acid; 4-Pyridinecarboxylic acid, 5-bromo-2-ethoxy-; Isonicotinic acid, 5-bromo-2-ethoxy-; 5-Bromo-2-ethoxypyridine-4-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-2-Ethoxyisonicotinic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the precise requirements of your research or production process. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and conformity to agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. Keep away from incompatible materials such as strong acids and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.