Description

Ethyl 6-Ethynylpicolinate is a high-purity, functionalized picolinate ester derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in the strategic combination of an ethynyl group and an ester moiety on the pyridine ring, enabling precise molecular construction for complex target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for applications in medicinal chemistry, material science, and the synthesis of novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in kinase inhibitor and other small-molecule drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of novel pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of specialty polymers, ligands for catalysis, and advanced organic materials.
• Chemical Biology Probes: Utilized in click chemistry applications due to the reactive ethynyl group, enabling bioconjugation and labeling strategies.
• Academic & Industrial R&D: A versatile reagent for methodological development and the synthesis of complex molecular architectures in research laboratories.

Basic Information

Product Name	Ethyl 6-Ethynylpicolinate
CAS No.	1379302-65-4
Molecular Formula	C10H9NO2
Molecular Weight	175.18 g/mol
Synonyms	Ethyl 6-ethynylpyridine-2-carboxylate; 6-Ethynylpicolinic acid ethyl ester; 2-Pyridinecarboxylic acid, 6-ethynyl-, ethyl ester; Ethyl 6-ethynyl-2-pyridinecarboxylate; Picolinic acid, 6-ethynyl-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 6-Ethynylpicolinate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed specifications for every shipment, supporting your quality assurance and regulatory compliance needs in R&D and production.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Keep away from oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.