Description

3-Bromo-2-Chloro-4-Nitropyridine is a high-purity halogenated and nitrated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and pesticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Synthesis: Serves as a starting material for creating sophisticated ligands used in transition metal catalysis and coordination chemistry.
• Material Science: Building block for organic electronic materials, such as those used in OLEDs and conductive polymers, due to its electron-deficient nitropyridine structure.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A valuable substrate for custom synthesis houses and CROs/CMOs serving the life sciences sector.

Basic Information

Product Name	3-Bromo-2-Chloro-4-Nitropyridine
CAS No.	1379301-97-9
Molecular Formula	C5H2BrClN2O2
Molecular Weight	237.44 g/mol
Synonyms	2-Chloro-3-bromo-4-nitropyridine; 4-Nitro-3-bromo-2-chloropyridine; 3-Bromo-2-chloro-4-nitropyridine; Pyridine, 3-bromo-2-chloro-4-nitro-; 1379301-97-9
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-2-Chloro-4-Nitropyridine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request, supporting compliance in GMP-aligned applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.