Description

Methyl 5-Bromo-3-Iodo-2-Methylbenzoate is a high-purity, multi-halogenated aromatic ester building block essential for advanced organic synthesis. This compound is valued for its unique substitution pattern, which provides multiple reactive sites for selective cross-coupling and functionalization reactions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting complex heterocycles.
• Agrochemical Research: Used to construct advanced active ingredients for crop protection products, leveraging its halogen handles for diversification.
• Material Science: Serves as a monomer or functional unit in the development of specialty polymers and advanced organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki-Miyaura, Stille, and other palladium-catalyzed coupling reactions due to the presence of both bromo and iodo substituents.
• Chemical Biology: Employed as a probe or linker in bioconjugation strategies and the development of chemical tools.
• Academic & Contract Research: A valuable reagent for methodological development and discovery chemistry in university and CRO laboratories.

Basic Information

Product Name	Methyl 5-Bromo-3-Iodo-2-Methylbenzoate
CAS No.	1378861-84-7
Molecular Formula	C9H8BrIO2
Molecular Weight	354.97 g/mol
Synonyms	Methyl 5-bromo-3-iodo-2-methylbenzoate; 5-Bromo-3-iodo-2-methylbenzoic acid methyl ester; Benzoic acid, 5-bromo-3-iodo-2-methyl-, methyl ester; 2-Methyl-5-bromo-3-iodobenzoic acid methyl ester; Methyl 2-methyl-5-bromo-3-iodobenzoate
EINECS	Contact for details

Quality Control

Our Methyl 5-Bromo-3-Iodo-2-Methylbenzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.