Description

Spiro[3.4]Octan-1-Amine CAS NO 1378527-98-0 is a specialized spirocyclic amine building block of significant interest in advanced organic synthesis. Its unique three-dimensional structure offers distinct advantages for modulating the physicochemical properties and biological activity of target molecules. This high-value intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disease research.
• Agrochemical Synthesis: Used in the development of new-generation pesticides and herbicides, where its spirocyclic core can enhance stability and efficacy.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Incorporated into specialty polymers and advanced organic frameworks to impart specific structural and functional characteristics.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies for bespoke synthesis projects requiring high-purity, complex amine intermediates.

Basic Information

Product Name	Spiro[3.4]Octan-1-Amine
CAS No.	1378527-98-0
Molecular Formula	C8H15N
Molecular Weight	125.21 g/mol
Synonyms	1-Aminospiro[3.4]octane; Spiro[3.4]octan-1-amine; 1-Azaspiro[3.4]octane; 1-Spiro[3.4]octylamine; 1378527-98-0; Spirocyclic C8 amine
EINECS	Contact for details

Quality Control

Our Spiro[3.4]Octan-1-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.