Description

3-Methyl-4-(2,2,2-Trifluoro-Acetylamino)-Benzoic Acid Methyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its trifluoroacetyl-protected amino benzoate structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) and complex organic molecules. It serves as a key building block for scientists and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for complex synthetic pathways.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, or metabolic diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its unique fluorine-containing moiety for enhanced biological activity and stability.
• Organic Synthesis Reagent: Serves as a protected amino acid derivative or a specialized ester in complex organic transformations, including peptide coupling and heterocycle formation.
• Material Science Precursor: Potential use in the synthesis of specialty polymers, liquid crystals, or organic electronic materials due to its aromatic and fluorinated components.
• Academic & Contract Research: Essential for university laboratories and Contract Research Organizations (CROs) conducting exploratory research in synthetic methodology and medicinal chemistry.

Basic Information

Product Name	3-Methyl-4-(2,2,2-Trifluoro-Acetylamino)-Benzoic Acid Methyl Ester
CAS No.	1378449-54-7
Molecular Formula	C11H10F3NO3
Molecular Weight	261.20 g/mol
Synonyms	Methyl 3-Methyl-4-[(2,2,2-trifluoroacetyl)amino]benzoate; 4-(Trifluoroacetamido)-3-methylbenzoic Acid Methyl Ester; Benzoic acid, 3-methyl-4-[(2,2,2-trifluoroacetyl)amino]-, methyl ester; Methyl 4-(2,2,2-trifluoroacetamido)-3-methylbenzoate; 3-Methyl-4-trifluoroacetamidobenzoic Acid Methyl Ester; TFAB-ME (abbreviation); 1378449-54-7
EINECS	Contact for details

Quality Control

Our production of 3-Methyl-4-(2,2,2-Trifluoro-Acetylamino)-Benzoic Acid Methyl Ester adheres to stringent quality management protocols. Every batch is analyzed using advanced techniques like HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality systems are designed to support cGMP (current Good Manufacturing Practice) standards for pharmaceutical intermediate applications, ensuring traceability and reliability for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single unknown impurity	≤0.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.