Description

3-Chloro-2-(Methylthio)-5-(Trifluoromethyl)Pyridine is a high-purity, advanced pharmaceutical intermediate and agrochemical building block. This compound is valued for its unique heterocyclic structure, which incorporates chlorine, sulfur, and trifluoromethyl functional groups, enabling precise chemical modifications. It is primarily utilized by R&D chemists and process development scientists in the life sciences and crop protection industries for synthesizing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in antiviral and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Critical precursor in the manufacturing of advanced pesticides and herbicides, leveraging the bioactivity of the pyridine core.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry and process chemistry optimization in laboratory settings.
• Material Science: Potential monomer or additive for creating specialty polymers with specific electronic or surface properties.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and commercial production under cGMP guidelines.

Basic Information

Product Name	3-Chloro-2-(Methylthio)-5-(Trifluoromethyl)Pyridine
CAS No.	1378308-91-8
Molecular Formula	C7H5ClF3NS
Molecular Weight	227.63 g/mol
Synonyms	3-Chloro-2-(methylthio)-5-(trifluoromethyl)pyridine; 2-Methylthio-3-chloro-5-trifluoromethylpyridine; 5-(Trifluoromethyl)-3-chloro-2-methylthiopyridine; 3-Chloro-2-methylsulfanyl-5-trifluoromethylpyridine; Pyridine, 3-chloro-2-(methylthio)-5-(trifluoromethyl)-; 1378308-91-8
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-(Methylthio)-5-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with ISO standards and meets the stringent requirements for pharmaceutical and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids, strong bases, and strong oxidizing agents. The compound may be moisture-sensitive; keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.