Description

Methyl 4-Cyano-2,6-Difluorobenzoate is a high-purity, multi-functional aromatic ester building block. This compound is valued for its unique molecular architecture, featuring both cyano and difluoro substituents, which makes it a versatile intermediate in advanced synthetic chemistry. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex active molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the difluoro and cyano groups contribute to biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of specialty chemicals for electronic displays, leveraging its aromatic core and functional groups for molecular tuning.
• Organic Synthesis & Research: Employed as a versatile reagent in academic and industrial laboratories for cross-coupling reactions, hydrolysis to carboxylic acids, and further functional group transformations.
• Polymer Modifier: Acts as a monomer or additive in the synthesis of specialty polymers to introduce specific chemical resistance or optical properties.

Basic Information

Product Name	Methyl 4-Cyano-2,6-Difluorobenzoate
CAS No.	1376259-20-9
Molecular Formula	C9H5F2NO2
Molecular Weight	197.14 g/mol
Synonyms	Methyl 2,6-Difluoro-4-cyanobenzoate; 4-Cyano-2,6-difluorobenzoic Acid Methyl Ester; Benzoic acid, 4-cyano-2,6-difluoro-, methyl ester; Methyl 4-Cyano-2,6-Difluorobenzoate; 2,6-Difluoro-4-cyanobenzoic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our Methyl 4-Cyano-2,6-Difluorobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP and ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.