Description

trans-(1R,2R)-2-tert-Butoxycarbonylaminocyclopentanecarboxylic Acid Ethyl Ester is a high-purity, enantiomerically pure chiral building block of significant importance in advanced organic synthesis. This compound matters because it provides a stereochemically defined scaffold for constructing complex molecules, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, including protease inhibitors and other small molecule drugs.
• Peptidomimetic Synthesis: Serves as a constrained, cyclic amino acid derivative for constructing peptide analogs with enhanced metabolic stability and bioavailability.
• Asymmetric Synthesis: Used as a starting material or auxiliary in catalytic asymmetric reactions to introduce defined stereocenters.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Agrochemical Research: Potential intermediate in the development of enantiomerically pure agrochemicals, such as herbicides or fungicides.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) laboratories for methodological development and discovery chemistry.

Basic Information

Product Name	trans-(1R,2R)-2-tert-Butoxycarbonylaminocyclopentanecarboxylic Acid Ethyl Ester
CAS No.	1375312-86-9
Molecular Formula	C14H25NO4
Molecular Weight	271.35 g/mol
Synonyms	(1R,2R)-2-[(tert-Butoxycarbonyl)amino]cyclopentanecarboxylic Acid Ethyl Ester; Ethyl (1R,2R)-2-[(tert-Butoxycarbonyl)amino]cyclopentanecarboxylate; Boc-(1R,2R)-ACPC-OEt; trans-2-(Boc-amino)cyclopentanecarboxylic Acid Ethyl Ester; (1R,2R)-N-Boc-2-aminocyclopentanecarboxylic Acid Ethyl Ester; (1R,2R)-2-(Boc-amino)cyclopentane-1-carboxylic Acid Ethyl Ester; Ethyl trans-(1R,2R)-2-(Boc-amino)cyclopentanecarboxylate
EINECS	Contact for details

Quality Control

Our trans-(1R,2R)-2-tert-Butoxycarbonylaminocyclopentanecarboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for demanding research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.