Description

(6-(Difluoromethoxy)Pyridin-3-Yl)Methanol is a high-value pyridine derivative and versatile chemical building block characterized by its difluoromethoxy and hydroxymethyl functional groups. This compound is essential for advanced organic synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of drug candidates, particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the difluoromethoxy group can enhance biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials with specific electronic or surface properties.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	(6-(Difluoromethoxy)Pyridin-3-Yl)Methanol
CAS No.	1375098-07-9
Molecular Formula	C7H7F2NO2
Molecular Weight	175.13 g/mol
Synonyms	3-Pyridinemethanol, 6-(difluoromethoxy)-; 6-(Difluoromethoxy)-3-pyridinemethanol; (6-(Difluoromethoxy)pyridin-3-yl)methanol; 5-(Hydroxymethyl)-2-(difluoromethoxy)pyridine; 2-(Difluoromethoxy)-5-(hydroxymethyl)pyridine; 6-Difluoromethoxynicotinyl alcohol
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our chemical intermediates. Production of (6-(Difluoromethoxy)Pyridin-3-Yl)Methanol follows current Good Manufacturing Practices (cGMP) where applicable, with purity typically exceeding 97% (by HPLC). Every batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles to ensure consistency and reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.