Description

5-[4-Fluoro-3-(Trifluoromethyl)Phenyl]-2-Methoxypyridine is a high-value, multi-fluorinated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is engineered to introduce specific steric and electronic properties into target molecules, making it indispensable for research and development in demanding fields. It is primarily sought after by pharmaceutical, agrochemical, and advanced materials scientists for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides and fungicides, where the fluorine and trifluoromethyl groups enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis for asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and other functional materials requiring tailored electronic properties.
• Chemical Biology Probes: Utilized as a core structure for designing molecular probes and tags to study biological processes.

Basic Information

Product Name	5-[4-Fluoro-3-(Trifluoromethyl)Phenyl]-2-Methoxypyridine
CAS No.	1375069-20-7
Molecular Formula	C13H9F4NO
Molecular Weight	271.21 g/mol
Synonyms	2-Methoxy-5-[4-fluoro-3-(trifluoromethyl)phenyl]pyridine; 5-(4-Fluoro-3-(trifluoromethyl)phenyl)-2-methoxypyridine; 2-Methoxy-5-(4-fluoro-3-trifluoromethylphenyl)pyridine; 1375069-20-7; 5-(4-Fluoro-3-trifluoromethylphenyl)-2-methoxypyridine
EINECS	Contact for details

Quality Control

Our production of 5-[4-Fluoro-3-(Trifluoromethyl)Phenyl]-2-Methoxypyridine adheres to stringent quality management protocols. Each batch is characterized and tested to ensure identity, purity, and consistency, meeting the exacting standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥97% by HPLC), identity confirmation, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.