Description

Ethyl 2-Bromopyrrole-1-Carboxylate is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for its reactive bromine and ester functionalities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of pyrrole-containing drug candidates, including kinase inhibitors and receptor antagonists.
• Agrochemical Research: Used in the development of novel pesticides and herbicides that leverage the pyrrole scaffold for biological activity.
• Material Science: Serves as a monomer or precursor for conductive polymers, organic semiconductors, and advanced functional materials.
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and as a substrate for further functionalization of the pyrrole ring.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and the exploration of new heterocyclic compounds.

Basic Information

Product Name	Ethyl 2-Bromopyrrole-1-Carboxylate
CAS No.	1375064-62-2
Molecular Formula	C7H8BrNO2
Molecular Weight	218.05 g/mol
Synonyms	1-Carbethoxy-2-bromopyrrole; Ethyl 2-bromo-1H-pyrrole-1-carboxylate; 2-Bromo-1-(ethoxycarbonyl)pyrrole; 2-Bromopyrrole-1-carboxylic acid ethyl ester; 1H-Pyrrole-1-carboxylic acid, 2-bromo-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-Bromopyrrole-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are provided with every shipment. We adhere to cGMP guidelines for the production of intermediates intended for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.