Description

tert-Butyl 2,8-Dioxa-5-Azaspiro[3.5]Nonane-5-Carboxylate is a high-value, spirocyclic building block and protected amine intermediate of significant interest in advanced organic synthesis. Its unique heterocyclic scaffold is crucial for constructing complex molecular architectures with precise three-dimensional control. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides that require specific spirocyclic motifs for bioactivity.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for designing molecular probes, enzyme inhibitors, and linkers in bioconjugation chemistry.
• Material Science Research: Employed in the synthesis of specialty polymers and functional organic materials with tailored properties.
• Academic & Contract Research: A valuable reagent for methodological development and exploring new synthetic routes in academic and industrial R&D laboratories.

Basic Information

Product Name	tert-Butyl 2,8-Dioxa-5-Azaspiro[3.5]Nonane-5-Carboxylate
CAS No.	1374658-90-8
Molecular Formula	C11H19NO4
Molecular Weight	229.27 g/mol
Synonyms	5-Boc-2,8-dioxa-5-azaspiro[3.5]nonane; tert-Butyl 2,8-dioxa-5-azaspiro[3.5]nonane-5-carboxylate; 2,8-Dioxa-5-azaspiro[3.5]nonane-5-carboxylic acid, 1,1-dimethylethyl ester; Boc-Protected 2,8-Dioxa-5-Azaspiro[3.5]Nonane; 5-(tert-Butoxycarbonyl)-2,8-dioxa-5-azaspiro[3.5]nonane; Spirocyclic Boc-Amine Ether
EINECS	Contact for details

Quality Control

Our tert-Butyl 2,8-Dioxa-5-Azaspiro[3.5]Nonane-5-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical characterization, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for all shipments, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.