Description

Methyl 4-(Benzylamino)-6-Chloronicotinate is a high-purity, advanced pharmaceutical intermediate characterized by its specific chloronicotinate structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and other fine chemicals, offering a key building block for medicinal chemistry research and development. It is primarily utilized by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-quality intermediates for scale-up and commercial manufacturing.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in kinase inhibitor and other targeted therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its chloronicotinate core.
• Chemical Research & Development: Serves as a versatile precursor for organic synthesis and method development in academic and industrial labs.
• Fine Chemical Production: Employed in the manufacture of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	Methyl 4-(Benzylamino)-6-Chloronicotinate
CAS No.	1374215-05-0
Molecular Formula	C14H13ClN2O2
Molecular Weight	276.72 g/mol
Synonyms	6-Chloro-4-(benzylamino)nicotinic acid methyl ester; Methyl 6-chloro-4-(phenylmethylamino)-3-pyridinecarboxylate; 4-(Benzylamino)-6-chloronicotinic acid methyl ester; 3-Pyridinecarboxylic acid, 6-chloro-4-[(phenylmethyl)amino]-, methyl ester; Methyl 4-(benzylamino)-6-chloro-3-pyridinecarboxylate; 6-Chloro-4-(benzylamino)-3-pyridinecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 4-(Benzylamino)-6-Chloronicotinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, confirming compliance with customer requirements and internal standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed to minimize exposure to atmospheric moisture and light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.