Description

2,6-Dichloro-4-Cyclopropylpyridine is a high-purity, halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring a cyclopropyl substituent, makes it a valuable intermediate for constructing complex molecules with specific steric and electronic properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents, including herbicides and fungicides, where the cyclopropyl group enhances biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized organic materials and liquid crystals due to its rigid, substituted pyridine core.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological systems and enzyme mechanisms.

Basic Information

Product Name	2,6-Dichloro-4-Cyclopropylpyridine
CAS No.	1374143-99-3
Molecular Formula	C8H7Cl2N
Molecular Weight	188.05 g/mol
Synonyms	4-Cyclopropyl-2,6-dichloropyridine; 2,6-Dichloro-4-cyclopropylpyridine; Pyridine, 2,6-dichloro-4-cyclopropyl-; 1374143-99-3; 4-Cyclopropyl-2,6-dichloro-pyridine
EINECS	Contact for details

Quality Control

Our 2,6-Dichloro-4-Cyclopropylpyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to cGMP principles and rigorous in-process controls guarantees a reliable supply of this high-value intermediate for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.