Description

2,6-Dimethoxy-3-(Trimethylsilyl)Pyridine is a high-value, functionalized pyridine derivative that serves as a versatile building block in advanced organic synthesis. Its unique structure, featuring both methoxy and trimethylsilyl protecting groups, makes it a critical intermediate for constructing complex molecules with precise regiochemistry. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly for constructing complex heterocyclic cores found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its functional groups for selective chemical transformations.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials and functional polymers where its silicon group can influence material properties.
• Cross-Coupling Reactions: Acts as a substrate or directing group in palladium-catalyzed cross-coupling reactions, such as Suzuki or Stille couplings.
• Protecting Group Strategy: The trimethylsilyl group provides a temporary protective function in multi-step synthetic pathways, allowing for sequential functionalization.

Basic Information

Product Name	2,6-Dimethoxy-3-(Trimethylsilyl)Pyridine
CAS No.	1373693-69-6
Molecular Formula	C10H17NO2Si
Molecular Weight	211.33 g/mol
Synonyms	3-(Trimethylsilyl)-2,6-dimethoxypyridine; 2,6-Dimethoxy-3-(trimethylsilyl)pyridine; Pyridine, 2,6-dimethoxy-3-(trimethylsilyl)-; 2,6-Dimethoxy-3-trimethylsilylpyridine; 3-TMS-2,6-dimethoxypyridine
EINECS	Contact for details

Quality Control

Our 2,6-Dimethoxy-3-(Trimethylsilyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.