Description

Ethyl Rac-(1R,5S,6R)-3-Azabicyclo[3.1.0]Hexane-6-Carboxylate Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique, strained bicyclic scaffold. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of central nervous system (CNS) and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates, particularly those targeting neurological pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis to explore new chemical entities.
• Process Chemistry Development: Serves as a critical starting material or intermediate in scaling up synthetic routes from laboratory to pilot and commercial scale.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for studies in organic synthesis methodology and drug discovery.

Basic Information

Product Name	Ethyl Rac-(1R,5S,6R)-3-Azabicyclo[3.1.0]Hexane-6-Carboxylate Hydrochloride
CAS No.	1373253-19-0
Molecular Formula	C10H16ClNO2
Molecular Weight	217.69 g/mol
Synonyms	Ethyl 3-Azabicyclo[3.1.0]hexane-6-carboxylate hydrochloride (racemic); (±)-Ethyl (1R,5S,6R)-3-azabicyclo[3.1.0]hexane-6-carboxylate hydrochloride; rac-Ethyl 3-azabicyclo[3.1.0]hexane-6-carboxylate HCl; 3-Azabicyclo[3.1.0]hexane-6-carboxylic acid, ethyl ester, hydrochloride; Ethyl 3-azabicyclo[3.1.0]hexane-6-carboxylate HCl salt
EINECS	Contact for details

Quality Control

Our Ethyl Rac-(1R,5S,6R)-3-Azabicyclo[3.1.0]Hexane-6-Carboxylate Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.