Description

5-Amino-3-(trifluoromethyl)pyridin-2(1H)-one is a high-value, heterocyclic organic compound featuring a reactive amino group and a stable trifluoromethyl substituent. This unique structure makes it a critical pharmaceutical intermediate and building block for advanced agrochemicals and specialty materials. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Serves as a vital building block for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Material Science: Used in the research and production of advanced polymers, liquid crystals, and electronic materials where the trifluoromethyl group imparts desirable properties like thermal stability and lipophilicity.
• Chemical Research & Development: Employed as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Fluorinated Compound Production: Acts as a specialized feedstock for synthesizing other complex fluorinated organic molecules used in various high-tech applications.

Basic Information

Product Name	5-Amino-3-(trifluoromethyl)pyridin-2(1H)-one
CAS No.	1373232-58-6
Molecular Formula	C6H5F3N2O
Molecular Weight	178.11 g/mol
Synonyms	5-Amino-3-(trifluoromethyl)-2(1H)-pyridinone; 5-Amino-3-(trifluoromethyl)-1H-pyridin-2-one; 2-Hydroxy-5-amino-3-(trifluoromethyl)pyridine; 3-(Trifluoromethyl)-5-aminopyridin-2(1H)-one; 5-Amino-3-trifluoromethyl-1H-pyridin-2-one; 5-Amino-3-(trifluoromethyl)-2-hydroxypyridine
EINECS	Contact for details

Quality Control

Our production of 5-Amino-3-(trifluoromethyl)pyridin-2(1H)-one adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets exacting research and commercial-grade specifications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.