Description

5-Amino-3-Bromopyridine-2-Thiol is a versatile heterocyclic building block featuring a reactive thiol group and amino functionality. This compound matters for its role as a critical intermediate in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Ligand Precursor: Serves as a precursor for metal-chelating ligands in catalysis and material science.
• Functional Material Development: Employed in the research of organic semiconductors, conductive polymers, and advanced dyes.
• Chemical Biology Probes: Utilized for creating biochemical probes and labeled compounds for diagnostic and research applications.
• Cross-Coupling Reactions: Acts as a substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions.

Basic Information

Product Name	5-Amino-3-Bromopyridine-2-Thiol
CAS No.	1373232-57-5
Molecular Formula	C5H5BrN2S
Molecular Weight	205.08 g/mol
Synonyms	2-Mercapto-5-amino-3-bromopyridine; 3-Bromo-5-aminopyridine-2-thiol; 5-Amino-3-bromo-2-pyridinethiol; 3-Bromo-5-amino-2-mercaptopyridine; 2-Pyridinethiol, 5-amino-3-bromo-; 5-Amino-3-bromo-2-thiopyridinol; 3-Bromopyridine-2-thiol, 5-amino-
EINECS	Contact for details

Quality Control

Our 5-Amino-3-Bromopyridine-2-Thiol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.