Description

5-Aza-Spiro[2.4]Heptane-7-Carboxylic Acid Methyl Ester is a high-value, spirocyclic building block featuring a constrained bicyclic structure. This compound is critical for medicinal chemistry research, enabling the synthesis of novel molecules with potential therapeutic applications. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers for developing new drug candidates, particularly in areas requiring rigid, three-dimensional scaffolds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and metabolic disorder targets.
• Medicinal Chemistry Research: Used to introduce conformational restraint into lead compounds, improving potency, selectivity, and metabolic stability during drug discovery.
• Chemical Biology Probes: Serves as a scaffold for developing tool compounds and probes to study enzyme function and biological pathways.
• Agrochemical Synthesis: Potential intermediate in the research and development of new crop protection agents with novel modes of action.
• Academic & Contract Research: Employed in universities and CROs for methodological development and exploring new chemical spaces in organic synthesis.

Basic Information

Product Name	5-Aza-Spiro[2.4]Heptane-7-Carboxylic Acid Methyl Ester
CAS No.	1373223-43-8
Molecular Formula	C8H11NO2
Molecular Weight	153.18 g/mol
Synonyms	Methyl 5-azaspiro[2.4]heptane-7-carboxylate; 5-Azaspiro[2.4]heptane-7-carboxylic acid, methyl ester; 7-Methoxycarbonyl-5-azaspiro[2.4]heptane; Azaspiroheptane Carboxylate Ester; Spiro[cyclopropane-1,2'-pyrrolidine]-5'-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 5-Aza-Spiro[2.4]Heptane-7-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the exacting standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.