Description

4-Bromo-5-Iodo-2-Methyl-Benzoic Acid Methyl Ester is a high-purity, multi-halogenated aromatic building block of significant interest in advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. This compound is essential for medicinal chemists and process development scientists working on novel active ingredients, where it serves as a versatile precursor for cross-coupling reactions and further functionalization.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with specific modes of action.
• Material Science: Serves as a monomer or precursor for specialty polymers and liquid crystals with tailored electronic properties.
• Chemical Synthesis: A versatile substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create complex biaryl systems.
• Ligand & Catalyst Development: Useful for synthesizing novel chelating ligands used in homogeneous catalysis.
• Academic & R&D: Employed in research laboratories for methodological studies and exploring new synthetic pathways.

Basic Information

Product Name	4-Bromo-5-Iodo-2-Methyl-Benzoic Acid Methyl Ester
CAS No.	1370600-57-9
Molecular Formula	C9H8BrIO2
Molecular Weight	354.97 g/mol
Synonyms	Methyl 4-Bromo-5-Iodo-2-Methylbenzoate; 2-Methyl-4-bromo-5-iodobenzoic Acid Methyl Ester; Benzoic acid, 4-bromo-5-iodo-2-methyl-, methyl ester; 4-Bromo-5-iodo-o-toluic Acid Methyl Ester; Methyl 4-Bromo-5-iodo-2-methylbenzoate; CAS 1370600-57-9
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-5-Iodo-2-Methyl-Benzoic Acid Methyl Ester is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot upon request, supporting your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.