Description

3-Bromo-5-Iodo-2-Methyl Benzoic Acid Methyl Ester is a high-purity, multi-halogenated aromatic building block of significant interest in advanced organic synthesis. Its unique substitution pattern makes it a valuable precursor for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. This compound is primarily sought by R&D chemists and process development scientists working on novel active ingredients, functional materials, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the halogenated aromatic core contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLEDs and semiconductors, due to its halogenated, electron-deficient structure.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.
• Academic Research: Utilized in university and institutional labs for methodological studies in halogenation, esterification, and cross-coupling chemistry.

Basic Information

Product Name	3-Bromo-5-Iodo-2-Methyl Benzoic Acid Methyl Ester
CAS No.	1370600-52-4
Molecular Formula	C9H8BrIO2
Molecular Weight	354.97 g/mol
Synonyms	Methyl 3-Bromo-5-iodo-2-methylbenzoate; Benzoic acid, 3-bromo-5-iodo-2-methyl-, methyl ester; 2-Methyl-3-bromo-5-iodobenzoic acid methyl ester; 3-Bromo-5-iodo-o-toluic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-5-Iodo-2-Methyl Benzoic Acid Methyl Ester is produced and tested under a strict quality management system. We guarantee high chemical purity and consistency, supported by comprehensive analytical documentation. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to ensure it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.