Description

Ethyl 2-(tert-Butoxycarbonylamino)-4,5,6,7-Tetrahydrobenzo[D]Thiazole-4-Carboxylate CAS NO 1369897-34-6 is a high-purity, advanced pharmaceutical intermediate featuring a protected amino group and a fused tetrahydrobenzothiazole scaffold. This compound is critical for the synthesis of complex bioactive molecules, offering precise chemical functionality for targeted molecular construction. It is primarily required by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly in the areas of central nervous system (CNS) and oncology research.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those targeting neurological pathways.
• Protease Inhibitor Research: Used in the development of inhibitors for various enzymatic targets due to its specific molecular architecture.
• Chemical Biology Probes: Serves as a precursor for creating labeled compounds used in mechanism-of-action studies.
• Peptidomimetic Synthesis: Integral for constructing non-peptide scaffolds that mimic peptide structures for enhanced stability and bioavailability.
• Academic & Contract Research: Employed in university and CRO laboratories for exploratory medicinal chemistry and hit-to-lead optimization programs.
• Scale-up Process Development: Used in pilot plants to develop and optimize scalable synthetic routes for potential Active Pharmaceutical Ingredients (APIs).

Basic Information

Product Name	Ethyl 2-(tert-Butoxycarbonylamino)-4,5,6,7-Tetrahydrobenzo[D]Thiazole-4-Carboxylate
CAS No.	1369897-34-6
Molecular Formula	C15H22N2O4S
Molecular Weight	326.41 g/mol
Synonyms	Ethyl 2-((tert-Butoxycarbonyl)amino)-4,5,6,7-tetrahydrobenzo[d]thiazole-4-carboxylate; 2-(Boc-amino)-4,5,6,7-tetrahydrobenzo[d]thiazole-4-carboxylic acid ethyl ester; 4,5,6,7-Tetrahydrobenzo[d]thiazole-4-carboxylic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-, ethyl ester; Boc-Amino-Tetrahydrobenzothiazole Ethyl Ester; 1369897-34-6; Ethyl 2-(N-Boc-amino)-4,5,6,7-tetrahydrobenzothiazole-4-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 2-(tert-Butoxycarbonylamino)-4,5,6,7-Tetrahydrobenzo[D]Thiazole-4-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); therefore, the container must be kept tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.