Description

[1,2,4]Triazolo[1,5-A]Pyridine-2-Methanamine is a high-value nitrogen-containing heterocyclic building block, specifically a fused triazolopyridine derivative. This compound is critical for medicinal chemistry and pharmaceutical research, serving as a versatile scaffold for the development of novel active pharmaceutical ingredients (APIs). It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand Synthesis in Catalysis: Employed to create sophisticated nitrogen-donor ligands for transition metal catalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science: Investigated for the development of organic electronic materials, such as electron-transport layers or luminescent compounds.
• Chemical Biology Probes: Utilized to construct molecular probes for studying enzyme function and biological pathways due to its ability to mimic natural heterocycles.

Basic Information

Product Name	[1,2,4]Triazolo[1,5-A]Pyridine-2-Methanamine
CAS No.	1369412-53-2
Molecular Formula	C8H8N4
Molecular Weight	160.18 g/mol
Synonyms	1,2,4-Triazolo[1,5-a]pyridine-2-methanamine; 2-(Aminomethyl)-[1,2,4]triazolo[1,5-a]pyridine; [1,2,4]Triazolo[1,5-a]pyridin-2-ylmethanamine; (1,2,4-Triazolo[1,5-a]pyridin-2-yl)methanamine; 2-(Aminomethyl)-1,2,4-triazolo[1,5-a]pyridine; Triazolopyridine-2-methanamine; 1369412-53-2 (CAS)
EINECS	Contact for details

Quality Control

Our [1,2,4]Triazolo[1,5-A]Pyridine-2-Methanamine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.