Description

5'-Bromo-1',3'-Dihydrospiro[Cyclopropane-1,2'-Indene]-3'-Amine is a high-value, spirocyclic organic building block featuring a bromine substituent and a primary amine functional group. This compound is critical for medicinal chemistry research and development, enabling the synthesis of novel, structurally complex molecules. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers for applications in drug discovery and advanced material science.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and oncology therapeutics.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to explore new chemical entities and biological targets.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands in catalysis and molecular recognition applications.
• Advanced Material Science: Incorporated into the design of organic semiconductors, liquid crystals, or other functional materials requiring rigid, three-dimensional scaffolds.
• Agrochemical Development: Potential intermediate in the research and synthesis of new crop protection agents with novel modes of action.

Basic Information

Product Name	5'-Bromo-1',3'-Dihydrospiro[Cyclopropane-1,2'-Indene]-3'-Amine
CAS No.	1368900-12-2
Molecular Formula	C11H12BrN
Molecular Weight	238.12 g/mol
Synonyms	5'-Bromo-1',3'-dihydrospiro[cyclopropane-1,2'-inden]-3'-amine; 5'-Bromospiro[cyclopropane-1,2'-indene]-3'-amine; 5-Bromo-1,3-dihydrospiro[cyclopropane-1,2'-inden]-3-amine; 1368900-12-2; 5'-Bromo-1',3'-dihydrospiro[cyclopropane-1,2'-indene]-3'-amine; 5'-Bromo-1',3'-dihydrospiro[cyclopropane-1,2'-indene]-3'-amine (CAS 1368900-12-2); Spiro[cyclopropane-1,2'-indene]-3'-amine, 5'-bromo-1',3'-dihydro-
EINECS	Contact for details

Quality Control

Our 5'-Bromo-1',3'-Dihydrospiro[Cyclopropane-1,2'-Indene]-3'-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and chemical identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.