Description

5-Oxaspiro[2.5]octan-8-one is a specialized spirocyclic lactone building block of significant interest in advanced organic synthesis. Its unique bridged structure, featuring both an oxirane and a lactone moiety, makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly those requiring spirocyclic or constrained ring systems.
• Agrochemical Synthesis: Building block for creating new herbicides, fungicides, and insecticides with unique modes of action.
• Material Science Research: Monomer or precursor for developing specialized polymers with tailored thermal or mechanical properties.
• Asymmetric Catalysis: Chiral pool starting material or ligand precursor for stereoselective synthesis.
• Natural Product Analog Synthesis: Used to mimic or modify complex natural product cores containing fused oxygen heterocycles.
• Cross-Coupling Reactions: Serves as an electrophilic partner in various metal-catalyzed coupling reactions to introduce functional complexity.

Basic Information

Product Name	5-Oxaspiro[2.5]octan-8-one
CAS No.	1368764-75-3
Molecular Formula	C7H10O2
Molecular Weight	126.15 g/mol
Synonyms	5-Oxaspiro[2.5]octan-8-one; 8-Oxa-1-azaspiro[4.5]decan-2-one (related structural isomer); Spiro[oxirane-2,2'-oxolan]-3'-one; Oxaspirooctanone; Epoxy-tetrahydrofuranone; CAS 1368764-75-3
EINECS	Contact for details

Quality Control

Our 5-Oxaspiro[2.5]octan-8-one is produced under strict quality management protocols. Each batch undergoes comprehensive analytical characterization, including NMR, HPLC, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full batch-specific data are provided to guarantee the material meets your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be sensitive to prolonged exposure to moisture and strong bases.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.