Description

tert-Butyl 5-Hydroxy-2,9-diazaspiro[5.5]undecane-2-carboxylate (Wx102580) is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic diaza scaffold. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with targeted biological activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of central nervous system (CNS) therapeutics and other small molecule drugs. Its structural complexity demands stringent quality control to ensure batch-to-batch consistency and optimal performance in downstream synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• API Development: Serves as a critical building block in the route development and scale-up of Active Pharmaceutical Ingredients (APIs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for exploring new synthetic methodologies and biological mechanisms.

Basic Information

Product Name	tert-Butyl 5-Hydroxy-2,9-diazaspiro[5.5]undecane-2-carboxylate (Wx102580)
CAS No.	1368038-01-0
Molecular Formula	C14H26N2O3
Molecular Weight	270.37 g/mol
Synonyms	2,9-Diazaspiro[5.5]undecane-2-carboxylic acid, 5-hydroxy-, 1,1-dimethylethyl ester; tert-Butyl 5-hydroxy-2,9-diazaspiro[5.5]undecane-2-carboxylate; WX-102580; Wx102580; 5-Hydroxy-2,9-diazaspiro[5.5]undecane-2-carboxylic acid tert-butyl ester; 1368038-01-0
EINECS	Contact for details

Quality Control

Our tert-Butyl 5-Hydroxy-2,9-diazaspiro[5.5]undecane-2-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and conformity to client specifications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and pre-clinical development phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.