Description

5-Oxaspiro[3.5]Nonan-8-One is a high-value, specialized spirocyclic ketone building block used in advanced organic synthesis. This compound is critical for the development of novel pharmaceuticals and agrochemicals due to its unique three-dimensional structure, which provides access to complex molecular architectures. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing key intermediates in active ingredient synthesis.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its spirocyclic scaffold for bioactivity.
• Fine Chemical Production: Serves as a precursor for creating complex fragrance and flavor molecules, as well as other specialty chemicals.
• Material Science Research: Investigated as a monomer or cross-linking agent for developing polymers with specific thermal or mechanical properties.
• Academic & Contract Research: Employed in academic laboratories and CROs (Contract Research Organizations) for methodological studies and library synthesis in medicinal chemistry.

Basic Information

Product Name	5-Oxaspiro[3.5]Nonan-8-One
CAS No.	1367945-40-1
Molecular Formula	C8H12O2
Molecular Weight	140.18 g/mol
Synonyms	5-Oxaspiro[3.5]nonan-8-one; 8-Oxaspiro[4.4]nonan-1-one; Spiro[3.5]nonane-8-one, 5-oxa-; Tetrahydro-4H-pyran-4-spirocyclopentanone; Oxaspiro[3.5]nonan-8-one
EINECS	Contact for details

Quality Control

Our 5-Oxaspiro[3.5]Nonan-8-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.