Description

4-Bromo-[1,2,3]triazolo[1,5-a]pyridine is a high-value brominated heterocyclic building block, specifically a functionalized triazolopyridine derivative. This compound is of significant interest for its role as a key intermediate in modern pharmaceutical discovery and materials science research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries to construct complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the triazolopyridine scaffold's bioactivity.
• Material Science: Serves as a precursor for creating organic electronic materials, such as ligands for OLEDs and other optoelectronic devices.
• Chemical Biology & Proteomics: Employed as a versatile handle for bioconjugation and the development of chemical probes to study biological systems.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Sonogashira, and Buchwald-Hartwig cross-coupling reactions to introduce the triazolopyridine moiety.
• Ligand Synthesis: Used to prepare novel nitrogen-donor ligands for catalysis and coordination chemistry.

Basic Information

Product Name	4-Bromo-[1,2,3]triazolo[1,5-a]pyridine
CAS No.	1367827-91-5
Molecular Formula	C6H4BrN3
Molecular Weight	198.02 g/mol
Synonyms	4-Bromo[1,2,3]triazolo[1,5-a]pyridine; 4-Bromo-1,2,3-triazolo[1,5-a]pyridine; 4-Bromotriazolopyridine; 4-Bromo-[1,2,3]triazolopyridine; 4-Bromo-1H-[1,2,3]triazolo[1,5-a]pyridine; 4-Bromo-s-triazolo[1,5-a]pyridine; 1367827-91-5
EINECS	Contact for details

Quality Control

Our 4-Bromo-[1,2,3]triazolo[1,5-a]pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. This product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.