Description

tert-Butyl 2-Oxa-5,8-Diazaspiro[3.5]Nonane-8-Carboxylate is a high-value, heterocyclic building block featuring a spirocyclic scaffold. This compound is a critical intermediate in modern pharmaceutical research and development, enabling the synthesis of complex molecules with potential therapeutic activity. It is primarily sought after by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for constructing novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Medicinal Chemistry Scaffold: Used to explore structure-activity relationships (SAR) due to its rigid, three-dimensional spirocyclic structure, which can improve drug-like properties.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a versatile linker or component in the design of bifunctional molecules for targeted protein degradation.
• Chemical Biology Probes: Employed in the creation of tool compounds for studying biological pathways and target validation.
• Agrochemical Research: Potential intermediate in the development of new pesticides or herbicides with novel modes of action.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) settings for exploratory synthetic chemistry and method development.

Basic Information

Product Name	tert-Butyl 2-Oxa-5,8-Diazaspiro[3.5]Nonane-8-Carboxylate
CAS No.	1367777-12-5
Molecular Formula	C11H20N2O3
Molecular Weight	228.29 g/mol
Synonyms	8-Boc-2-oxa-5,8-diazaspiro[3.5]nonane; tert-Butyl 2-oxa-5,8-diazaspiro[3.5]nonane-8-carboxylate; 2-Oxa-5,8-diazaspiro[3.5]nonane-8-carboxylic acid tert-butyl ester; 8-(tert-Butoxycarbonyl)-2-oxa-5,8-diazaspiro[3.5]nonane; Boc-2-oxa-5,8-diazaspiro[3.5]nonane; 1367777-12-5; 2-Oxa-5,8-diazaspiro[3.5]nonane, 8-[(1,1-dimethylethoxy)carbonyl]-
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Oxa-5,8-Diazaspiro[3.5]Nonane-8-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and chemical identity consistent with pharmaceutical intermediate standards. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent degradation. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.