Description

2,8-Dichloro-7-Nitro-1,5-Naphthyridine is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique substitution pattern makes it a valuable precursor for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. This compound is primarily sought after by R&D chemists and process development scientists working on novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antimicrobial research.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a precursor for the synthesis of functionalized naphthyridine-based polymers, ligands, and organic electronic materials.
• Chemical Biology: Employed as a molecular probe or scaffold in the design of enzyme inhibitors and receptor modulators.
• Academic & Contract Research: Utilized in universities and CROs for methodological studies and the discovery of new chemical entities.
• Custom Synthesis: A starting material for the contract manufacturing of complex, customer-specific fine chemicals.

Basic Information

Product Name	2,8-Dichloro-7-Nitro-1,5-Naphthyridine
CAS No.	1366050-48-7
Molecular Formula	C8H3Cl2N3O2
Molecular Weight	244.04 g/mol
Synonyms	7-Nitro-2,8-dichloro-1,5-naphthyridine; 1,5-Naphthyridine, 2,8-dichloro-7-nitro-; 2,8-Dichloro-7-nitro-1,5-naphthyridine; 1366050-48-7; Dichloronitronaphthyridine
EINECS	Contact for details

Quality Control

Every batch of 2,8-Dichloro-7-Nitro-1,5-Naphthyridine is manufactured and tested under strict quality management systems to ensure batch-to-batch consistency and high purity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.