Description

Methyl (2Z)-3-(3-Bromo-1H-1,2,4-Triazol-5-Yl)Acrylate CAS NO 1365988-78-8 is a high-purity, functionalized acrylate derivative containing both a brominated triazole moiety and an acrylate ester group. This unique bifunctional structure makes it a versatile and critical building block in advanced organic synthesis, particularly for the development of novel pharmacologically active compounds and specialty polymers. It is primarily needed by pharmaceutical R&D teams, agrochemical researchers, and material scientists working on next-generation active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates, especially those targeting kinase inhibition and other enzymatic pathways.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Polymer Modification: Acts as a functional monomer for creating specialty polymers with tailored properties like UV-absorption, bioactivity, or enhanced adhesion.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Material Science Research: Utilized in developing advanced coatings, resins, and composites with specific performance characteristics.
• Cross-coupling Reactions: The bromo-triazole group makes it a suitable substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).

Basic Information

Product Name	Methyl (2Z)-3-(3-Bromo-1H-1,2,4-Triazol-5-Yl)Acrylate
CAS No.	1365988-78-8
Molecular Formula	C7H6BrN3O2
Molecular Weight	244.05 g/mol
Synonyms	Methyl (Z)-3-(3-Bromo-1H-1,2,4-triazol-5-yl)acrylate; Methyl 3-(3-Bromo-1H-1,2,4-triazol-5-yl)-2-propenoate; (Z)-Methyl 3-(3-bromo-1H-1,2,4-triazol-5-yl)acrylate; 3-Bromo-1H-1,2,4-triazol-5-yl acrylic acid methyl ester; 1365988-78-8; Methyl 3-(3-bromo-1H-1,2,4-triazol-5-yl)propenoate; (2Z)-3-(3-Bromo-1H-1,2,4-triazol-5-yl)-2-propenoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl (2Z)-3-(3-Bromo-1H-1,2,4-Triazol-5-Yl)Acrylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.