Description

Ethyl 3,3-Difluoro-2-Hydroxypent-4-Enoate CAS NO 1365970-40-6 is a high-value fluorinated building block characterized by its unique combination of an enoate ester and a difluorinated hydroxy group. This compound is critical for the synthesis of complex molecules where the introduction of fluorine atoms can dramatically alter biological activity, metabolic stability, and physicochemical properties. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in protease inhibitors, kinase inhibitors, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where fluorination enhances lipophilicity and environmental stability.
• Material Science Precursor: Serves as a building block for specialty polymers and advanced materials that require fluorinated segments for specific performance characteristics.
• Organic Synthesis Reagent: Employed in medicinal and synthetic chemistry for Michael additions, cyclization reactions, and the construction of complex, fluorinated heterocycles.
• Fluorine Chemistry Research: An essential compound for academic and industrial research exploring new methodologies in selective fluorination and asymmetric synthesis.

Basic Information

Product Name	Ethyl 3,3-Difluoro-2-Hydroxypent-4-Enoate
CAS No.	1365970-40-6
Molecular Formula	C7H10F2O3
Molecular Weight	180.15 g/mol
Synonyms	Ethyl 3,3-difluoro-2-hydroxy-4-pentenoate; 4-Pentenoic acid, 3,3-difluoro-2-hydroxy-, ethyl ester; 3,3-Difluoro-2-hydroxypent-4-enoic acid ethyl ester; 1365970-40-6; Ethyl 3,3-difluoro-2-hydroxypent-4-enoate; 2-Hydroxy-3,3-difluoropent-4-enoic acid ethyl ester
EINECS	Contact for details

Quality Control

Every batch of Ethyl 3,3-Difluoro-2-Hydroxypent-4-Enoate is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids, strong bases, and oxidizing agents. The container must be kept tightly closed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.