Description

1,4-Bis-[4-[4-Methyl-3-[[4-(Pyridin-3-Yl)Pyrimidin-2-Yl]Amino]Phenyl]Carbamoyl]Benzylpiperazine is a sophisticated, high-purity organic compound designed for advanced research and development applications. This molecule is valued for its complex heterocyclic structure, which makes it a critical intermediate or building block in the synthesis of novel pharmaceutical candidates. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in drug discovery programs, particularly those focused on kinase inhibition and targeted therapies.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs) for investigational drugs.
• Kinase Inhibitor Research: Used in the development and optimization of novel kinase inhibitor compounds due to its pyrimidine and pyridine motifs.
• Chemical Biology Probes: Employed in the creation of molecular probes for studying specific biological pathways and target validation.
• High-Throughput Screening (HTS): Utilized as a reference compound or library component in drug discovery screening assays.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of specialized, non-commercial quantities.
• Academic & Institutional Research: Supports fundamental chemical and pharmacological research in university and government laboratories.

Basic Information

Product Name	1,4-Bis-[4-[4-Methyl-3-[[4-(Pyridin-3-Yl)Pyrimidin-2-Yl]Amino]Phenyl]Carbamoyl]Benzylpiperazine
CAS No.	1365802-18-1
Molecular Formula	C48H46N10O2
Molecular Weight	794.96 g/mol
Synonyms	1,4-Bis(4-{[4-methyl-3-({4-(pyridin-3-yl)pyrimidin-2-yl}amino)phenyl]carbamoyl}benzyl)piperazine; 1,4-Bis(4-((4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)carbamoyl)benzyl)piperazine; 1365802-18-1; UNII-9J0K9F2V1H; 9J0K9F2V1H; 1,4-Bis[4-[[[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]amino]carbonyl]benzyl]piperazine; 1,4-Bis(4-{[4-methyl-3-({4-(3-pyridinyl)-2-pyrimidinyl}amino)phenyl]carbamoyl}benzyl)piperazine
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch undergoes comprehensive analytical characterization using techniques such as HPLC, NMR, and mass spectrometry to ensure structural identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical quality attributes. We support development projects requiring material produced under GMP-like conditions for non-clinical studies, with specifications tailored to your project phase.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.