Description

2-Benzyl-6-Oxo-2-Aza-Spiro[3.3]Heptane is a high-value, synthetically versatile spirocyclic building block. This compound is a critical intermediate in modern pharmaceutical research and development, particularly for constructing complex molecular architectures. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical space due to its constrained spirocyclic scaffold.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential linker or component in the design of bifunctional molecules for targeted protein degradation.
• Agrochemical Research: Employed in the synthesis of advanced crop protection agents with novel modes of action.
• Chemical Biology Probes: Utilized to create tool compounds for investigating biological pathways and protein function.
• Academic & Contract Research: A valuable reagent for synthetic methodology development and exploration of new heterocyclic chemistry in academic and CRO settings.

Basic Information

Product Name	2-Benzyl-6-Oxo-2-Aza-Spiro[3.3]Heptane
CAS No.	1365639-14-0
Molecular Formula	C13H15NO
Molecular Weight	201.27 g/mol
Synonyms	2-Benzyl-2-azaspiro[3.3]heptan-6-one; 2-Azaspiro[3.3]heptan-6-one, 2-benzyl-; 2-Benzyl-6-oxo-2-azaspiro[3.3]heptane; 2-Benzyl-2-aza-spiro[3.3]heptan-6-one; 1365639-14-0; 2-Benzyl-2-azaspiro[3.3]heptane-6-one; Spiro[3.3]heptane-6-one, 2-benzyl-2-aza-
EINECS	Contact for details

Quality Control

Our 2-Benzyl-6-Oxo-2-Aza-Spiro[3.3]Heptane is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency, meeting the stringent requirements for advanced research intermediates. Certificates of Analysis (COA) with detailed HPLC, NMR, and MS data are provided to guarantee reliable and reproducible performance in your synthetic workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.