Description

2-Azaspiro[3.3]heptane oxylate is a high-value, nitrogen-containing spirocyclic building block with the CAS number 1365639-13-9. This compound is prized for its unique three-dimensional structure, which is critical for modulating the physicochemical properties and biological activity of advanced molecules. It is an essential intermediate for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder therapeutic areas.

Application

• Pharmaceutical Intermediate: A key spirocyclic scaffold in the synthesis of novel drug candidates targeting neurological and psychiatric disorders.
• Medicinal Chemistry R&D: Used to introduce structural complexity and improve drug-like properties such as solubility and metabolic stability in lead optimization.
• Agrochemical Synthesis: Serves as a precursor for developing new crop protection agents with novel modes of action.
• Ligand and Catalyst Development: Employed in the design of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized to create tool compounds for studying biological pathways and protein function.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific thermal or mechanical properties.

Basic Information

Product Name	2-Azaspiro[3.3]heptane Oxylate
CAS No.	1365639-13-9
Molecular Formula	C7H11NO3
Molecular Weight	157.17 g/mol
Synonyms	2-Azaspiro[3.3]heptane, 6-oxo-, oxalate (1:1); 2-Oxa-6-azaspiro[3.3]heptane oxalate; 6-Oxo-2-azaspiro[3.3]heptane oxalate; Azaspiroheptane oxalate; Spiro[cyclopropane-1,2'-pyrrolidine] oxalate derivative; 1-Oxa-4-azaspiro[2.3]hexane oxalate (tautomer); 1365639-13-9; 2-Azaspiro[3.3]heptan-6-one oxalate
EINECS	Contact for details

Quality Control

Our 2-Azaspiro[3.3]heptane oxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.