Description

7-Aza-Spiro[3.5]Nonan-2-One is a high-value, nitrogen-containing spirocyclic building block of significant interest in advanced organic synthesis. Its unique fused bicyclic structure, featuring a lactam moiety, makes it a versatile precursor for constructing complex molecular architectures. This compound is primarily utilized by pharmaceutical and agrochemical research organizations engaged in the development of novel active ingredients, where it serves as a critical scaffold for drug discovery and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and metabolic disease targets.
• Agrochemical Research: Used as a core scaffold in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Chemical Biology Probe Development: Serves as a versatile scaffold for creating molecular probes to study enzyme function and biological pathways.
• Material Science: Potential precursor for specialty polymers and advanced materials requiring rigid, nitrogen-doped frameworks.
• Academic & Contract Research: Employed in methodological studies and as a starting material for synthesizing complex natural product analogs and heterocyclic compounds.

Basic Information

Product Name	7-Aza-Spiro[3.5]Nonan-2-One
CAS No.	1365570-36-0
Molecular Formula	C8H13NO
Molecular Weight	139.19 g/mol
Synonyms	7-Azaspiro[3.5]nonan-2-one; 2-Oxo-7-azaspiro[3.5]nonane; 7-Aza-spiro[3.5]nonane-2-one; Azaspiro[3.5]nonan-2-one; 1-Azaspiro[4.4]nonan-8-one (tautomeric form); 7-Aza-2-oxaspiro[3.5]nonane (incorrect but common search variant); 1365570-36-0; 7-Azaniaspiro[3.5]nonan-2-one
EINECS	Contact for details

Quality Control

Our 7-Aza-Spiro[3.5]Nonan-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. We provide Certificates of Analysis (COA) with detailed specifications for trace impurities, residual solvents, and assay results. Our quality commitment supports applications requiring GMP-grade starting materials and compliance with ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the original container tightly sealed under an inert atmosphere to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.