Description

Methyl 1-(4-Bromophenyl)-3-Oxocyclobutanecarboxylate is a high-value, synthetically versatile cyclobutane derivative. This compound serves as a critical advanced intermediate in modern organic synthesis, enabling the construction of complex molecular architectures. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and anti-inflammatory agents.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging the structural motif of the substituted cyclobutanone.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the synthesis of specialized polymers with unique thermal or mechanical properties.
• Chemical Synthesis Reagent: Employed in [3+2] cycloadditions and ring-expansion reactions to access complex, strained carbocyclic systems.
• Academic & Contract Research: Essential for methodology development and exploration of new reaction pathways in university and CRO laboratory settings.

Basic Information

Product Name	Methyl 1-(4-Bromophenyl)-3-Oxocyclobutanecarboxylate
CAS No.	1364663-42-2
Molecular Formula	C12H11BrO3
Molecular Weight	283.12 g/mol
Synonyms	Methyl 1-(4-bromophenyl)-3-oxocyclobutanecarboxylate; 1-(4-Bromophenyl)-3-oxocyclobutanecarboxylic acid methyl ester; 3-Oxo-1-(4-bromophenyl)cyclobutanecarboxylic acid methyl ester; Methyl 3-oxo-1-(p-bromophenyl)cyclobutanecarboxylate; 1-(p-Bromophenyl)-3-oxocyclobutanecarboxylic acid methyl ester; Cyclobutanecarboxylic acid, 1-(4-bromophenyl)-3-oxo-, methyl ester
EINECS	Contact for details

Quality Control

Every batch of Methyl 1-(4-Bromophenyl)-3-Oxocyclobutanecarboxylate is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency essential for research and scale-up. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.