Description

tert-Butyl 5-Cyano-1H-Pyrrolo[3,2-B]Pyridine-1-Carboxylate is a high-value heterocyclic building block and protected intermediate essential for advanced pharmaceutical research and development. This compound is specifically designed to facilitate the synthesis of complex molecules, offering a versatile handle for further functionalization in medicinal chemistry. It is a critical reagent for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in kinase inhibitor research and other targeted therapies.
• Medicinal Chemistry: Used for structure-activity relationship (SAR) studies and lead optimization due to its reactive cyano and protected amine functionalities.
• Agrochemical Synthesis: Serves as a precursor in the development of new pesticides and herbicides with specific biological activity.
• Chemical Biology: Employed in the creation of molecular probes and tool compounds for studying biological pathways.
• Fine Chemical Production: Utilized in multi-step synthetic routes to produce complex, high-value specialty chemicals.
• Academic Research: A valuable reagent for universities and research institutes exploring new heterocyclic chemistry and reaction methodologies.

Basic Information

Product Name	tert-Butyl 5-Cyano-1H-Pyrrolo[3,2-B]Pyridine-1-Carboxylate
CAS No.	1364663-38-6
Molecular Formula	C13H13N3O2
Molecular Weight	243.26 g/mol
Synonyms	1-Boc-5-cyano-7-azaindole; 1-(tert-Butoxycarbonyl)-5-cyano-1H-pyrrolo[3,2-b]pyridine; 5-Cyano-1H-pyrrolo[3,2-b]pyridine-1-carboxylic acid tert-butyl ester; tert-Butyl 5-cyano-7-azaindole-1-carboxylate; 5-Cyano-1H-pyrrolo[3,2-b]pyridine-1-carboxylic acid 1,1-dimethylethyl ester; Boc-5-cyano-7-azaindole; 1364663-38-6
EINECS	Contact for details

Quality Control

Our tert-Butyl 5-Cyano-1H-Pyrrolo[3,2-B]Pyridine-1-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems support the stringent requirements of pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.