Description

Methyl 4,6-Dibromonicotinate is a high-purity brominated nicotinate derivative, serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of complex molecules, particularly in pharmaceutical research and agrochemical discovery. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel heterocyclic compounds and active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly kinase inhibitors and other biologically active nitrogen-containing heterocycles.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the bromine substituents for further functionalization.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials and functional polymers where the nicotinate core is integral.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	Methyl 4,6-Dibromonicotinate
CAS No.	1364663-27-3
Molecular Formula	C7H5Br2NO2
Molecular Weight	294.93 g/mol
Synonyms	4,6-Dibromonicotinic Acid Methyl Ester; Methyl 4,6-Dibromopyridine-3-carboxylate; 3-Pyridinecarboxylic Acid, 4,6-Dibromo-, Methyl Ester; 4,6-Dibromo-3-pyridinecarboxylic Acid Methyl Ester; Methyl 4,6-Dibromo-3-pyridinecarboxylate; 4,6-Dibromonicotinate Methyl Ester; 1364663-27-3 (CAS)
EINECS	Contact for details

Quality Control

Our Methyl 4,6-Dibromonicotinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and traceability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep container tightly sealed when not in use to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.