Description

6-Nitro-8-Trifluoromethyl-Imidazo[1,2-A]Pyridine-2-Carboxylic Acid Ethyl Ester is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. Its unique molecular architecture, featuring both nitro and trifluoromethyl substituents on the imidazopyridine core, makes it a critical intermediate for developing novel active compounds. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to incorporate these privileged pharmacophores into new molecular entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for targeting central nervous system (CNS) disorders, anti-infectives, and oncology applications.
• Agrochemical Research: Serves as a sophisticated building block for developing next-generation herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Used in the research of advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-deficient aromatic system.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global pharmaceutical clients.
• Academic & Institutional Research: Provides a versatile scaffold for methodological studies in organic chemistry, including novel cross-coupling and functionalization reactions.

Basic Information

Item	Detail
Product Name	6-Nitro-8-Trifluoromethyl-Imidazo[1,2-A]Pyridine-2-Carboxylic Acid Ethyl Ester
CAS No.	1363405-53-1
Molecular Formula	C11H8F3N3O4
Molecular Weight	303.20 g/mol
Synonyms	Ethyl 6-Nitro-8-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxylate; 6-Nitro-8-trifluoromethylimidazo[1,2-a]pyridine-2-carboxylic Acid Ethyl Ester; Imidazo[1,2-a]pyridine-2-carboxylic acid, 6-nitro-8-(trifluoromethyl)-, ethyl ester; 1363405-53-1; 8-Trifluoromethyl-6-nitro-imidazo[1,2-a]pyridine-2-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Every batch of 6-Nitro-8-Trifluoromethyl-Imidazo[1,2-A]Pyridine-2-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our products are developed to meet the stringent requirements of research and pre-clinical development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles by HPLC is provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area%)	≥ 98.0%
Single Maximum Impurity	≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.