Description

3-Amino-Oxetane-3-Carboxylic Acid Methyl Ester is a high-value, multifunctional oxetane building block essential for advanced organic synthesis. This compound is particularly significant for its role as a key precursor in the development of novel pharmaceuticals and bioactive molecules, enabling the introduction of constrained, three-dimensional structural motifs. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) disorders and other therapeutic areas.
• Proteolysis Targeting Chimera (PROTAC) Development: Used in the construction of linkers and warheads for bifunctional molecules designed for targeted protein degradation.
• Agrochemical Synthesis: Serves as a precursor for creating new-generation herbicides and insecticides with improved efficacy and environmental profiles.
• Peptidomimetics & Bioisosteres: Incorporates the rigid, polar oxetane ring to replace traditional peptide bonds or other functional groups, enhancing metabolic stability and binding affinity.
• Material Science Research: Employed in the synthesis of advanced polymers and functional materials with tailored thermal and mechanical properties.
• Chemical Biology Probes: Utilized to create tool compounds for studying enzyme function and biological pathways.

Basic Information

Product Name	3-Amino-Oxetane-3-Carboxylic Acid Methyl Ester
CAS No.	1363383-31-6
Molecular Formula	C5H9NO3
Molecular Weight	131.13 g/mol
Synonyms	Methyl 3-Aminooxetane-3-carboxylate; 3-Aminooxetane-3-carboxylic Acid Methyl Ester; 3-Amino-3-(methoxycarbonyl)oxetane; Oxetane-3-carboxylic acid, 3-amino-, methyl ester; Methyl 3-aminooxetane-3-carboxylate; 3-Carbomethoxy-3-aminooxetane; 3-Aminooxetane-3-methyl carboxylate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch of 3-Amino-Oxetane-3-Carboxylic Acid Methyl Ester is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) with detailed chromatographic data are available upon request. We adhere to cGMP principles for manufacturing to ensure batch-to-batch consistency suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.