Description

2-Azaspiro[4.5]Decane-7-Carboxylic Acid is a high-purity, specialized organic building block featuring a unique spirocyclic structure. This compound is of significant value in pharmaceutical research and development, serving as a critical intermediate for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of central nervous system (CNS) and other therapeutic agents.
• Medicinal Chemistry Research: Used in scaffold hopping and structure-activity relationship (SAR) studies to explore new chemical space.
• Peptidomimetics & Bioactive Molecule Synthesis: The spirocyclic carboxylic acid moiety is valuable for creating conformationally constrained analogs.
• Agrochemical Research: Serves as a building block for novel herbicides, fungicides, or insecticides with potential new modes of action.
• Ligand & Catalyst Development: Can be utilized in the synthesis of novel chiral ligands for asymmetric catalysis.
• Academic & Industrial R&D: Fundamental research in organic synthesis and methodology development.

Basic Information

Product Name	2-Azaspiro[4.5]Decane-7-Carboxylic Acid
CAS No.	1363382-89-1
Molecular Formula	C10H17NO2
Molecular Weight	183.25 g/mol
Synonyms	7-Carboxy-2-azaspiro[4.5]decane; 2-Azaspiro[4.5]decane-7-carboxylic acid; 7-Carboxy-2-azaspiro[4.5]decane; Azaspirodecane carboxylic acid; Spirocyclic proline derivative; 1-Aza-7-carboxyspiro[4.5]decane (tautomeric form); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 2-Azaspiro[4.5]Decane-7-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.