Description

Methyl 3-Methyl-1H-Pyrrolo[2,3-B]Pyridine-6-Carboxylate is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel pharmaceutical agents, particularly in kinase inhibitor research and other therapeutic areas. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for targeted cancer therapies.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing novel molecular libraries in drug discovery programs.
• Kinase Inhibitor Development: Serves as a core structural motif in the design and synthesis of potent and selective kinase inhibitors.
• Chemical Biology Probes: Employed in the creation of tool compounds for studying biological pathways and target validation.
• Process Chemistry & Scale-Up: Used in route scouting and optimization for the commercial-scale manufacturing of complex drug candidates.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting the pharmaceutical industry with custom synthesis.

Basic Information

Item	Details
Product Name	Methyl 3-Methyl-1H-Pyrrolo[2,3-B]Pyridine-6-Carboxylate
CAS No.	1363382-05-1
Molecular Formula	C10H10N2O2
Molecular Weight	190.20 g/mol
Synonyms	Methyl 3-Methyl-1H-pyrrolo[2,3-b]pyridine-6-carboxylate; 6-Methoxycarbonyl-3-methyl-1H-pyrrolo[2,3-b]pyridine; 3-Methyl-1H-pyrrolo[2,3-b]pyridine-6-carboxylic acid methyl ester; 1H-Pyrrolo[2,3-b]pyridine-6-carboxylic acid, 3-methyl-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-Methyl-1H-Pyrrolo[2,3-B]Pyridine-6-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We support compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.