Description

Methyl 4-Bromo-1H-Pyrazolo-[3,4-C]Pyridine-3-Carboxylate is a high-value brominated pyrazolopyridine derivative, serving as a critical synthetic intermediate in advanced organic chemistry. This compound matters for its role in constructing complex heterocyclic scaffolds, enabling the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for lead optimization and scale-up synthesis. The compound, identified by CAS number 1363381-48-9, is supplied with stringent quality control to ensure batch-to-batch consistency for demanding applications.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors and other small-molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used in creating novel fungicides and herbicides by leveraging its heterocyclic core for bioactivity.
• Chemical Biology Probe Development: Serves as a precursor for fluorescent tags or affinity probes to study biological processes.
• Material Science Precursor: Potential intermediate in the synthesis of organic electronic materials or metal-organic frameworks (MOFs).
• Academic & Contract Research: Essential for methodological development and novel synthetic route exploration in academic and CRO laboratories.
• Scale-up & Process Chemistry: Supplied in development and commercial quantities for process optimization and pilot plant campaigns.

Basic Information

Product Name	Methyl 4-Bromo-1H-Pyrazolo-[3,4-C]Pyridine-3-Carboxylate
CAS No.	1363381-48-9
Molecular Formula	C9H6BrN3O2
Molecular Weight	268.07 g/mol
Synonyms	Methyl 4-bromo-1H-pyrazolo[3,4-c]pyridine-3-carboxylate; 4-Bromo-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid methyl ester; 1H-Pyrazolo[3,4-c]pyridine-3-carboxylic acid, 4-bromo-, methyl ester; 1363381-48-9; Methyl 4-bromopyrazolo[3,4-c]pyridine-3-carboxylate; 4-Bromo-1H-pyrazolo[3,4-c]pyridine-3-carboxylate methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 4-Bromo-1H-Pyrazolo-[3,4-C]Pyridine-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ISO standards for pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to prevent degradation. Keep the container tightly sealed in a dry environment to minimize exposure to moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.