Description

8-Boc-2-Oxo-3-Oxa-1,8-Diaza-Spiro[5.5]Undecane is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic and oxadiazolidinone structure. This compound is critical for medicinal chemistry research and development, serving as a key building block for the synthesis of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing protease inhibitors and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex drug candidates, particularly those targeting enzymatic pathways.
• Protease Inhibitor Development: Serves as a core scaffold for the research and production of novel protease inhibitors, a significant class of antiviral and anticancer agents.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new chemical entities.
• Bioconjugation & Prodrug Synthesis: The Boc-protected amine group allows for selective deprotection and further functionalization in prodrug strategies.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological processes and target identification.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or research-grade conditions.

Basic Information

Product Name	8-Boc-2-Oxo-3-Oxa-1,8-Diaza-Spiro[5.5]Undecane
CAS No.	1363381-43-4
Molecular Formula	C₁₃H₂₁N₃O₄
Molecular Weight	283.32 g/mol
Synonyms	tert-Butyl 2-oxo-3-oxa-1,8-diazaspiro[5.5]undecane-8-carboxylate; 1,8-Diaza-3-oxaspiro[5.5]undecan-2-one, 8-Boc-protected; 8-(tert-Butoxycarbonyl)-2-oxo-3-oxa-1,8-diazaspiro[5.5]undecane; Boc-ODASU; Boc-protected Oxadiazaspiro Undecanone; 8-Boc-1,8-diaza-3-oxaspiro[5.5]undecan-2-one; CAS 1363381-43-4
EINECS	Contact for details

Quality Control

Our 8-Boc-2-Oxo-3-Oxa-1,8-Diaza-Spiro[5.5]Undecane is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) are available for every batch, detailing all relevant specifications to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.