Description

5-Aza-Spiro[3.4]Octane-2-Carboxylic Acid Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic structure. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with potential for improved pharmacokinetic properties. It is primarily needed by research and development teams in the pharmaceutical and biotechnology sectors for the development of new therapeutic agents, particularly in areas like enzyme inhibition and targeted protein degradation.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel small-molecule drugs.
• Proteolysis-Targeting Chimera (PROTAC) Development: Serves as a versatile linker or component in the design of bifunctional degraders.
• Enzyme Inhibitor Synthesis: Used in constructing potent and selective inhibitors for various enzymatic targets.
• Chemical Biology Research: Employed as a tool compound for probing biological pathways and protein function.
• Peptidomimetic Chemistry: Incorporated into peptide analogs to enhance metabolic stability and bioavailability.
• Library Synthesis for High-Throughput Screening: Used to generate diverse compound libraries for drug discovery campaigns.

Basic Information

Product Name	5-Aza-Spiro[3.4]Octane-2-Carboxylic Acid Hydrochloride
CAS No.	1363381-35-4
Molecular Formula	C8H13ClN2O2
Molecular Weight	204.65 g/mol
Synonyms	5-Azaspiro[3.4]octane-2-carboxylic acid hydrochloride; 2-Carboxy-5-azaspiro[3.4]octane hydrochloride; 5-Azaspiro[3.4]octane-2-carboxylic acid HCl; 1-Azaspiro[3.4]octane-2-carboxylic acid hydrochloride (tautomer); 5-Aza-spiro[3.4]octane-2-carboxylic acid hydrochloride salt; 1363381-35-4; 5-Aza-Spiro[3.4]Octane-2-Carboxylic Acid HCl
EINECS	Contact for details

Quality Control

Our 5-Aza-Spiro[3.4]Octane-2-Carboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccant use and a nitrogen atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.